Postpartum depression may be caused by several factors including:
- Increased levels of stress hormones
- Poor response to stress
- Changes in hormone levels
- Inadequate neurosteroid levels
- Genetic risk factors
- Neurocircuit dysfunction
- History of abuse
- Lack of support
- Poor or irregular diet
- Changes in social or professional life
- Poor or irregular sleep schedule
- Isolation and poor support
SYMPTOMS OF POSTPARTUM DEPRESSION CAN INCLUDE:
- Severe mood swings
- Feeling like you’re a “bad mother”
- Trouble sleeping or eating
- Fears about hurting yourself or others
- Suicidal thoughts or behaviors
ZULRESSO (BREXANOLONE) INTRAVENOUS INFUSION FOR POSTPARTUM DEPRESSION
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What to Expect with Treatment
Safety and Efficacy of Zulresso
Frequently Asked Questions about depression during and after pregnancy
How common are maternal mental health disorders?
Depression and Anxiety are the most common complications in pregnancy and postpartum. 1 in 7 women suffer from perinatal depression or anxiety. Only 15% of women will seek professional help.
Why don’t women get help?
There is a lack of awareness, screening and easy to access treatment. There is also ongoing stigma surrounding mental health issues and a fear that the baby will be taken away. Women spend a lot of time focused on their “birth plan”, including what pajamas they will wear in the hospital and what poses the birth photographer is going to use. Rarely, is treating or protecting one’s mental health part of the birth and postpartum plan. As women we have set unrealistically high expectations for childbirth and parenting and social media posting is contributing to the overall sense that we as women, and mothers, aren’t meeting expectations if everything isn’t perfect. Developing postpartum depression or anxiety wouldn’t be looked upon favorably by our peers so we don’t talk about it or get treatment. Talking about it opens conversations and helps to identify resources for women to access in their own communities.
What happens without treatment?
Postpartum depression occurs in 20% of postpartum moms and suicide is the most common cause of death in new moms. Without treatment depressed Moms are more likely to have impaired bonding with their babies. Untreated depression and anxiety during and after pregnancy can cause issues with children that are identifiable into adulthood including cognitive and developmental delays; poor self-control and aggression and an increase risk of substance abuse.
Are some women at higher risk for postpartum or maternal mental illness?
Yes, studies have identified certain genetic factors that increase risk of developing postpartum depression, it tends to run in families and women with a history of PMDD are at higher risk of postpartum mood and anxiety disorders. In addition; preexisting depression, anxiety or bipolar depression, a family history of mental illness, a personal history of trauma or abuse, experiencing a stressful event in the last year, an inadequate support system, financial stress, trouble breastfeeding and mom or baby with physical health issues during and after pregnancy.
What can someone do to decrease the risk of developing postpartum depression or anxiety?
In about 60 % of women, depression begins before or during pregnancy, so there is an opportunity to get into treatment before baby arrives. 40% of women don’t have symptoms until the postpartum period. The peak incidence is day 10-19 postpartum. In these women, it’s imperative that family members and health care providers are screening and talking about any concerns they have.
What treatments are available during pregnancy?
Interpersonal psychotherapy is highly effective in helping to develop a support system. Medication is helpful and has been shown to be safe in pregnancy. Risks of untreated mental health disorders are associated with poor health in the mom and baby. Healthy habits like exercise, eating a healthy diet and ensuring restful sleep can help as well. We encourage patients to create a maternal wellness plan to protect their postpartum mental health and be ready to address if it occurs.
What are the risks of medication during pregnancy?
We always need to balance and discuss the risks and benefits of medication treatment and risks of untreated depression. Untreated mental illness is more harmful than any prescribed medications, for mom and baby.
Are medications always required?
Not always, it depends on severity of symptoms and risk factors. We don’t want to wait until symptoms are so severe that hospitalization is required, we want to treat as soon as possible to get mom feeling back to her normal self and protect the mom and baby relationship.
CONCERNING SIGNS A PATIENT IS AT RISK FOR POSTPARTUM DEPRESSION
- Feeling sad, hopeless, empty, or overwhelmed
- Crying more often than usual or for no apparent reason
- Worrying or feeling overly anxious
Feeling moody, irritable, or restless
- Oversleeping, or being unable to sleep even when the baby is asleep
- Having trouble concentrating, remembering details, and making decisions
- Experiencing anger or rage
- Losing interest in activities that are usually enjoyable
- Physical aches and pains, including frequent headaches, stomach problems, and muscle pain
- Eating too little or too much
- Withdrawing from or avoiding friends and family
- Having trouble bonding or forming an emotional attachment with the baby
- Persistently doubting the ability to care for the baby
- Thinking about harming herself or the baby
- History of depression, anxiety/OCD or PPD
- History of PMDD
- Prior admission to inpatient psychiatry
- A history of bipolar disorder or psychosis
- Family history of mental illness
- History of or current trauma
- A stressful event in the last year
- Lack of help or support at home from partner or family members
- Significant financial stress
- History of infertility treatment
- Baby with colic, reflux or other health problems
- A history of previous miscarriage or stillbirth
- A history of diabetes, thyroid problems
- Being away from home country or culture
- Experienced health problems during pregnancy or childbirth